Bio Basic

Antibiotics

A modest selection of antibiotics are available, with a focus on culture related antibiotics. In liquid or powdered form.

Biochemicals

A wide array of biochemicals available: Adsorbents & Drying Agents, Amino Acids & Derivatives, Biological Buffers, Biology Reagents, Carbohydrates & Sugars, Detergents & Surfactants, Enzyme Inhibitors, Indicators & Stains, Nucleic Acids & Derivatives, Paraffins, pH Standards, Solvents, Vitamins, misc. Biochemicals.

Culture Media Reagent

A large variety of Culture Media and Culture Media related reagents are available: Agar, Broth, Growth Regulators, Herbicides, Indicators & Stains, Medium, Protein Expression, Supplements, Water, Culture Grade, and other.

Electrophoresis Reagent

A popular selection of products specialized for Electrophoresis: Acry & Bis-Acrylamide, Agarose, Blotting Papers, Buffers, Ethidium Bromide Disposal, Ladders (RNA/DNA/Protein), Precast Gels, Reagents, Reducing Agents, Tracking Dyes

Labware

A wide selection of labware available: Beakers, Bottles, Columns, Culture Related, Cuvettes, Cylinders, Dialysis Tubing & Membranes, Filtration Supplies, Lab Safety Equipment, Lab Supplies, Lab Accessories, Multicell Plates, Rack Boxes, Reagent Reservoirs, Tubes, Tube Boxes, Tube Racks.

Molecular Biology Kits

Offers high performing kits which maximize quality with significant savings in cost: Blunting & Ligation, Cell Transformation, Cloning, RNA (Extraction/mRNA Extraction/microRNA Extraction), DNA Extraction (Genomic), Protein (Extraction/Purification/Assays/ Staining), DNA & RNA & Protein - Extraction, Lysis, SDS Detection.

PCR Reagent

Supplying a wide range of PCR related reagents to help you with your research needs: dNMPs, dNTPs, dNTPs + Polymerase, Enzymes, NTPs, Nucleic Acid Co-precipitants, PCR Buers, PCR Kits (Cleanup/ Optimization/qRT-PCR/ RT-PCR/Tailing), PCR Premix (dPCR/qPCR/qRT-PCR/ RT-PCR), Vectors & Plasmids.

⠀Custom Service - DNA Sequencing

DNA Sequencing is the process of the reading precise sequence of nucleotides bases in a DNA molecule. Well equipped with specialty DNA Sequencing Facility laboratory equipment, Medigene provides reliable, customized DNA Sequencing Services to researchers at academic, biotechnology, clinical, government, pharmaceutical and other commercial industries in Malaysia. Besides being the best supplier of medical equipment, our excellence in science and DNA Sequencing Services, backed by state-of-the-art DNA Sequencing Facility made us capable to provide DNA Sequencing Services with speedy sample pick up, fast turn around at competitive rate. We are offering the following DNA Sequencing Services: - Large-scale DNA sequencing (>100 samples) - Small-scale DNA sequencing (<100 samples) - Plasmid DNA sequencing - PCR Products Sequencing - BAC, Fosmid, cosmid DNA sequencing Key Features - 3730XL sequencers - Sequence up to 1000bp per reaction, more than 90% successful rate - Special prices on large projects and contracts - Speedy turnaround - Incoming sample QC - Fluorescent dye-terminator sequencing - Universal primers provided at no additional charge (complete list) - Template preparation and primer synthesis available - Provide service support for problem sample Sample Requirement We accept plasmid DNA (150-200ng/ul, 15ul) and purified PCR products (15-20ng/ul, volume For plasmid sample, please specify vector name and insert length. >For PCR sample, please indicate the length of insert (bp). Please indicate the concentration of the primer enclosed with sample. The following primers are provided free of charge: M13+, M13-, T7, T3, T7 Terminator, SP6, pGEX5’, pGEX3', BGH rev. Samples are permanently destroyed after two months. How to Order Download and Email: You may download the Sequencing Order Form and email to info@mdgsb.com.my. For customers within Klang valley, please call to arrange for sample collection. For customers outside Klang valley, please send/courier the sample to: Chemopharm Sdn Bhd (Puchong Warehouse) No.11, Jalan TPP 5/1, Taman Perindustrian Puchong, 47100 Selangor, Malaysia Electronic Results sent after 96 hours to 168 hours. Terms & Conditions 1. Terms Medigene will send electronically DNA sequencing results to customers. All results will be kept in medigene data base for 6 months. During this period, customer may request for sequencing results. After 6 months, DNA sequencing results are automatically destroyed without further notification. DNA sequencing requests are only confirmed upon receipt of customer’s confirmation email or PO. 2. Turnaround Medigene will make its best effort to send DNA sequencing results within 168 hours. For larger projects, time will vary depending on the size of the project. We will try our best to accommodate special time constraints whenever possible, and projects of more than one hundred reactions may still get 168 hours turn around. Mail-in samples need to be received before 12.00 noon time to catch the oversea delivery. If you send the sample by courier service, please email the tracking number to info@mdgsb.com.my and ict@mdgsb.com.my 3. Cancellations Buyer may not cancel any order or return any samples without medigene’s consent. Cancellation and return charges may be imposed. Buyer is required to contact medigene to obtain a return material authorization number. 4. Warranty Medigene guarantees > 800bp Q20 read length and more than 90% successful rate. Medigene does not guarantee any downstream application(s) or usage of the DNA sequencing results. Any claims or dispute must be submitted within 2 weeks after shipment. At the time of shipment, medigene keeps a data base for unexpected incidents and/or disputes. Medigene reserves the right to refuse handling disputes after period of 3 months. 5. Prices Medigene unit prices for DNA sequencing tests apply only to the specific quantity, sample purification and primer synthesis. All prices are subject to correction of errors; medigene reserves the right to adjust prices on orders during production due to changes in cost of materials, transportation or wages. Failed runs will be charged in full however medigene will repeat failed samples at least once. Any sample that sequences with secondary structures will not be considered a failed reaction and will not be repeated. Any tax, customs, surcharge or duty, howsoever denominated, imposed upon the sale, importation, delivery or use of Products shall be the responsibility of Buyer.

⠀Custom Service - Gene Synthesis

Gene Synthesis is an efficient and cost effective custom gene production compared to traditional molecular clothing. Our Gene Synthesis Services include sequence design and optimization for your research, synthesis, clothing, verification and etc. Medigene is delighted to offer high quality Gene Synthesis Services at the most affordable prices. Medigene is delighted to offer high quality Gene Synthesis Services at the most affordable prices. Our Four Guarantee Commitment 1. 100% Correct DNA Sequencing Guarantee. - Each gene is confirmed base-by-base by sequence and is guaranteed to match 100% with your requested sequences. 2. Quick Turnaround Guarantee - Turnarounds are estimates. Further discount for large projects and long term contracts is available. Discount rates are based on total number of base pairs of gene order. Discount on long term contract is also available. 3. Lowest Price Guarantee - ALL customers are eligible for a promotional price at RM 2.90* per bp. Fully cloned and 100% sequence verified. *Limited time offer. *First time user only. Promotions valid in Malaysia only. *Only for standard sequences 3kb, large projects and Pharma account, please contact us for further details. Genes are cloned into standard vector pUC57. If customer desires to clone the gene into specified cloning vehicle, there is an additional fee of RM1000.00. We only provide single stranded sequencing. Double-stranded sequencing service is available upon request at no additional charge. 4. Absolute Confidentiality Guarantee How to Order Download and Email: You may download the Gene Synthesis Order Form and submit your order via e-mail to info@mdgsb.com.my Within 24 hours, you will receive a reply from one of our highly experienced customer representatives. Customer will receive 4ug of lyophilized DNA containing synthetic gene of interest, sequence chromatogram trace files, gene report, QC restriction digestion files, alignment file as well as vector information. If you wish to have up to 10ug of plasmid DNA, we are pleased to provide it to you at no extra cost. However, additional three days are required. Terms & Conditions 1. Terms - Medigene will deliver to customer 4.0ug plasmid DNA containing gene of interest. Plasmid DNA will be in pUC vector and provided in lyophilized powder form. Along with the final gene product, Medigene. will provide chromatogram sequencing results, gene report, alignment file, complete nucleotide sequence of the plasmid (cloning vector) including the sequence of the gene insert, and restriction digestion analysis results. All these documents will be copied on a CD sent along with the final product. Upon request, customer may also receive these documents electronically. - No gene synthesis is initiated without a PO number or letter/email. 2. Turnaround - Medigene will make its best effort to ship genes with a sequence length less than or equal to one thousand base pairs (1000bp), within ten (10) business days of receipt of an order. Medigene will make its best effort to ship genes with a sequence length between one thousand base pairs (1000bp) to two thousand base pairs (2000bp), within fifteen (15) business days of receipt of an order. For genes with a sequence length greater than two thousand base pairs (2000bp), Medigene will provide customer with an estimate of the completion date before manufacture of the gene. 3. High GC Content Genes and Highly Repetitive Genes In case of genes with high GC content (including regional high GC content genes), as well as highly repetitive genes, Medigene reserves the right to deliver genes within a more reasonable time frame. The new time frame will be consulted with customer prior to start of gene synthesis. Medigene may also refuse to fill any order by notifying customer orally or by written notice if the order is technically difficult to accomplish. 4. Custom Cloning Vehicle Medigene will charge an extra CDN$200 dollars to subclone the genes of interest into customer’s desired cloning vehicle. Customer must provide detailed sequence information pertaining customer vector. Any incorrect or false information provided by customer may lead to significant delay of the project. In this case, Medigeneis not responsible for the delay or any consequences caused by the delay. If subcloning fails due to circumstances beyond control, Medigene will deliver the final gene product in pUC57. $200 subcloning fee will NOT be charged to customer due to incompletion of subcloning process. 5. Genes with Expression Toxicity In the event that a designed DNA fragment is toxic to the E.coli host in which it is grown, Medigene reserves the right to provide 20ug of sequence-verified full length PCR fragment in place of plasmid DNA. Customer agrees to pay the full invoice amount. 6. Genes that Fail To Be Synthesized in Full Length in Standard Vector or as a PCR Fragment Medigene makes best effort to synthesize the full length gene in our standard vector pUC57. Should Medigene be unsuccessful in generating the full-length sequence in the standard vector or as a full length PCR fragment (due to sequence instability, toxicity, GC rich areas, repeats, etc.), client is not obligated to make ANY payment to Medigene. Should client be willing to receive sequence-verified PCR fragments, Medigene reserves the right to ask a proportion of the original price (up to 50%) to cover labour and material cost. 7. Cancellations - For any genes, customer may cancel the order after reaching an agreement with Medigene IF 7.1.Medigene has received the order, but has not initiated the project, customer is entitled to cancellation of the order without any penalty. 7.2.Medigene has prompted oligo synthesis, but not cloning and/or thereafter, customer may cancel the order, however, customer is obliged to pay 25% of the original price to cover labour and material cost. IF 7.3.Medigene has prompted oligo synthesis, and has started cloning and/or thereafter, customermay cancel the order, however, after agreement with Medigene. Customer is obliged to pay penalty cost, depending on the stage or status of the project. IF 7.4.Medigene has obtained the correct sequence within specified time frame, customer may cancel the order, however, with full amount paid to Medigene 8. Patents Medigene serves as a service provider and offers synthesis services of sequences provided by the customer. It is the sole responsibility of customer to verify whether their respective work is result of any infringements of any patents. Medigene expressly disclaims any liability in this regard. 9. Inspection Policy Upon receipt of shipped goods, customer shall inspect the shipment promptly for damages, shortages and correct identity of product. Any product that is not identical to the requested sequence will be replaced or authorized for return and credit, at our option. Any claims must be submitted within 3 months of shipment. 10. Warranty Medigene guarantees 100% accuracy and match of genes requested. Any claims must be submitted within 3 months of shipment. At the time of shipment, Medigene keeps a single copy of the gene for unexpected incidents and/or disputes. After 3 months, this copy of the gene will be destroyed permanently. Medigene reserves the right to refuse handling disputes after period of 3 months.

⠀Custom Service - Oligo Synthesis

Medigene is a one-stop-centre Oligo Synthesis Service Provider with fast turnaround time, for all types of oligonucleotides. We provide a comprehensive Oligo Synthesis Service that covered a multitude of synthesis scales, modifications, purifications and etc cater to match your researching needs. - Highest Purity at Lowest Price - Specializing in HAP* (High Affinity Purification) and PAGE Purification - Fast Services: Synthesis Completed within 36 Hours (for HAP* or PAGE) - All modified base oligos are purified by HPLC (WAVE system) - Highest QC and Quality Guaranteed High Affinity Purification (HAP) is a patented, novel purification method for custom oligos developed by Bio Basic Inc. DMT-ON-Oligo in the crude oligo mixture is first selectively absorbed on a high affinity resin in HAP column while incomplete oligos pass through. Final oligo is produced by removing the protection group of DMT under mild acidic conditions. HAP method provides two major advantages, high purity superior to De-Salted method (>98%), and low cost comparable to PAGE or HPLC methods. Oligos produced by the HAP method has such high purity that they can be directly used for any downstream experiments such as PCR, DNA Sequencing, Gene Synthesis, and Mutagenesis. At present, the most economic method to produce oligos is the De-Salted method, which however, yields products poor in purity. For example, the purity of 20-mer, 40-mer and 60-mer is approximately 68%, 45% and 30% respectively. This is calculated based on the 4 steps in DNA synthesis: De-DMT, Coupling, Oxidation and Capping. The average yield of each cycle is about 98%. The purity of 20-mer is therefore (0.98)20-1 = 68%; of 40-mer = (0.98)40-1 = 45%; and of 60-mer = (0.98)60-1 = 30%. Most laboratories use De-Salted oligos despite of their inferior purity because higher quality oligos produced by alternative methods such as PAGE, HPLC, and OPC are too costly. HAP presents the perfect alternative for high purity oligos at lowest prices. In fact, price is even lower than those of De-Salted method in some cases. How to Order Download and Email: You may download the Oligo Synthesis Order Form and submit your order via e-mail to info@mdgsb.com.my. Note: Please indicate scales, purification method, 5' end or 3' end modification. To guarantee quality, we do not carry De-salted oligos. HAP is a superior purification scale as compared to Desalt. Regular Oligo Synthesis

⠀Custom Service - Peptide Synthesis

Custom Peptide Synthesis is essential in biological, proteomic and drug discovery research. Medigene is Malaysia leading Peptide Synthesis Service Provider of high quality custom peptides. With state-of-the-art equipment backed by our experienced chemists, we provide a broad spectrum of Custom Peptide Synthesis Service and Protein Synthesis Service with detailed quality control documentation. - From small peptides to long peptides ( >100 amino acids) - From the regular peptides to all kinds of modified peptides - From mgs to kilograms - GMP standard peptides are available - All custom peptides are supplied with strict analytical specifications, which include HPLC and MS analysis. - Fast turnaround time. Most custom peptides can be delivered within 2-3 weeks. The delivery time may vary depending on the peptide length and nature of the sequences, as well as modifications. - Low price GUARANTEED. - All information is treated with strict confidentiality. If required, we are pleased to sign a client confidentiality agreement before receiving your compound structure. How to Order Download and Email: You may download the Peptide Synthesis Order Form and submit your order via e-mail to info@mdgsb.com.my. RUSH Service Do you need to RUSH order a peptide? We offer RUSH services at your needs. Peptides are ready in less than 5 days!!! Please contact us for price and details of this service. Regular Peptide Synthesis and Protein Modification

Our Brands