The evaluation of chromatograms poses a number of challenges for users in the analysis of MOSH/MOAH. Thomas Funke is one of the most experienced MOSH/MOAH experts in Germany. Under his leadership the software Chrolibri was developed for this special analysis.

Challenges of MOSH/MOAH analytics
An integration software for MOSH/MOAH analysis must solve various tasks that go beyond the normal integration of single peaks:

-Wide, chromatographically unresolved peak collections, so-called Humps or Unresolved Complex Mixtures (UCM), must be able to be integrated.
-Sharp peaks on these humps must be subtracted.
-It must be possible to divide the humps into retention time ranges that correlate with the chain length of n-alkanes. These individual ranges must be integrated separately.
-MOSH and MOAH chromatograms must be easily superimposed.
-Manual post-integration must be easily possible at any time.
-The baseline must be flexible and easily adaptable.
-It must be possible to subtract a blank value chromatogram.
-All these parameters must be flexibly configurable.

Chrolibri offers a solution for exactly these challenges.

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