NanoLC 400

NanoLC 400: A low flow LC-MS solution

The ideal choice for any workflow

The NanoLC 400 series enables a full range of analytical workflows that drive the identification of novel biomarkers or the quantification of small molecules and biologics to advance precision medicine research.

This front-end system consistently delivers accurate retention times, reproducible injection down to 200 nL and covers a broad range of flow rates.

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NanoLC 400 : Nanoflow LC enables you to dive deep into proteomics research with mere nanoliters of sample. However, if you’re also looking for a flexible system and range for more robustness and throughput, then the NanoLC 400 series is the right front-end to your ESI-MS. Developed specifically for nanospray mass spectrometry (MS), our NanoLC systems provide speed, sensitivity, resolution, and reliability for your research.

Product Highlights:

  • Models – NanoLC 415 for basic direct-to-column or trap-and-elute workflows & NanoLC 425 for more advanced 2D workflows
  • Column Oven – Compatible with the OptiFlow® Turbo V column oven. Column oven provides excellent retention time reproducibility by ensuring consistent column temperature
  • Flow Rates – Multiple flow rate options with user-interchangable plug-and-play flow modules to switch between nanoflow (100 nl/min – 1 µl/min) and microflow (1 – 10, or 5 -50 µl/min)
  • Flow Accuracy – SCIEX’s patented multifluidic flow control technology, for consistent, accurate retention times without flow-splitting
  • Software – Integrated and controlled with SCIEX Analyst® Software

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